Synaptic Compensation Driven by Action Potential-Independent Vesicle Release

[peterawenner]

Material below summarizes the article, Spontaneous Release Regulates Synaptic Scaling in the Embryonic Spinal Network In Vivo, published on July 6, 2016 in JNeurosci and authored by Miguel Angel Garcia-Bereguiain, Carlos Gonzalez-Islas, Casie Lindsly, and Peter Wenner.

Neural networks must balance excitation and inhibition throughout development and maturity. Many neural disorders are associated with an imbalance of excitation and inhibition, including spasticity, seizure activity, and several neurodevelopmental disorders.

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