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Scientific Rigor and the Quest for Truth


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Scientific rigor means implementing the highest standards and best practices of the scientific method and applying those to one’s research. It is all about discovering the truth.

Scientific rigor involves minimizing bias in subject selection and data analysis. It is about determining the appropriate sample size for your study so that you have sufficient statistical power to be more confident about whether you are generating false positives or missing out on false negatives. It’s about conducting research that has a good chance of being replicated in your own lab and other laboratories.

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  • 3 months later...
holmberg.kristina

I agree that scientific rigor and truth is always very important and should always be part of how we conduct our experiments and who we are as scientists. We have to keep in mind that data we generate may be used as a source to explore possible medical benefits and be part of the justification to why a certain drug should be tested in humans. I think it is important to think beyond the pre-clinical space and look at how your own data may drive development of new medicines forward. In addition to choosing the correct methodology, it is equally important to document what, how and when we did an experiment, and perhaps we all need a reminder about the patients out there who are waiting for a drug that will improve their quality of life.

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