Different Repulsive Receptors Take the Same Action

[longhongms]

Material below summarizes the article, Equivalent Activity of Repulsive Axon Guidance Receptors, published on January 27, 2016, in The Journal of Neuroscience and authored by Hong Long, Shingo Yoshikawa, and John B. Thomas.

In the developing nervous system, differentiating neurons send out axons to find and synapse with their targets: either other neurons or muscle cells, often located far away. Highly motile structures called growths cones, located at the leading edge of elongating axons, respond to guidance cues in their environment by changing the direction of axon growth.

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