HIF-1α and Multiple Sclerosis: A Case Not Yet Proven

[kakassoglou]

In biomedical research, as in many aspects of life, things are not always as simple as they first seem. It’s easy to start barking up the wrong tree. Our recent work exposed one of those “trees” in multiple sclerosis (MS): We found that a specific protein called hypoxia-inducible factor-1α, or HIF-1α, is likely not a main culprit in MS. However, we did learn a lot about what HIF-1α does in disease processes in the nervous system.

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