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  1. Have you checked out SfN's eNeuro Blog? Read the newest article and let us know your thoughts! Reviewing Editor Karl Herrup, PhD selected this paper and explains why he considers it noteworthy. While aggregates of the microtubule associated protein tau have been associated with Alzheimer's disease (AD) since its first description, there are aspects of the tau/Alzheimer's relationship that are difficult to understand. Tau hyper-phosphorylation facilitates its aggregation in vitro and the anatomic sites of tau aggregates correlate well with the loss of cognitive function. While these observations have held up well, it has always been a puzzle why the same post-translational phosphorylations of the tau protein that characterize the pathological aggregates found in the Alzheimer's brain are also found, without consequence, during fetal development. Betters et al. report differences in proteins interacting with tau between fetal brain and both adult and AD brain that were not found between adult control and AD brain. Furthermore, the interaction between 14-3-3 and tau was primarily associated with 4R tau, which is lacking in fetal brain. The study does not solve the problem entirely but does offer an important advance that should be of interest to the field. Read the full article: Characterization of the Tau Interactome in Human Brain Reveals Isoform-Dependent Interaction with 14-3-3 Family Proteins Ryan K. Betters, Emma Luhmann, Amy C. Gottschalk, Zhen Xu, Mallory R. Shin, Christopher P. Ptak, Kimberly L. Fiock, Lilliana C. Radoshevich, and Marco M. Hefti Category: Editor's Pick Tags: Disorders of the Nervous System, Neuroscience Research
  2. Dear Members, Past few weeks I have been occupied in organising a 3-hours long symposium and I felt that I should share my experience with you all. Collaboration in India is challenging and so I started working on additional research activities. Last year I saw an advertisement by Indian Academy of Neuroscience (IAN-2016) for the symposium call. I decided to organise and so I approached the organisers and they told me to have 4-5 speakers from India or abroad. So the steps I started to follow were as follows: First step, i worked on a symposium title and abstract. Second step, i did is that i made a list of potential scientist working in my research domain and I started sending them an invitation. Third step, after some acceptance from people I send an email. I submitted my proposal to the organisers. Fourth step, after the acceptance of my proposal I asked all the speakers to provide their abstract to me. Fifth Step, while attending the symposium I build connections and scientific networks with scientists working in both human and animal studies. While following these steps I learned that it was not that hard to organise the symposium. It only required a proper planning and direction. I encourage you fellow scientist to look for such opportunities in your respective countries because such activities will be good for collaborations and research experience. Please let me know what you all think about it?
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