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Showing results for tags 'brain'.
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Enhancing the Utility of Basic Research for Advancing CNS Therapeutics
Bianca Williams posted an event in Community Calendar
untilREGISTER HERE! Brain disorders are highly prevalent and substantially contribute to the overall global disease burden, yet the vast majority of compounds for these disorders that have been advanced to clinical testing were later abandoned due to a lack of clinical efficacy. While there are multiple reasons for clinical failure, one of the most frequently cited is the translational validity and overall quality of the data used as the basis for clinical research. In this webinar, we will define the concept of translation, discuss how various types of preclinical research contribute to the drug development process, as well as present some of the tools that have been developed in recent years to improve the translation of innovative ideas from academic research to patient care. Finally, we will discuss a case example of where these practices have been put into place to advance scientific translation. -
Extended Q&A: Exercise in Brain Health and Disease This resource has been adapted from the webinar, Exercise in Brain Health and Disease, which took place on April 28, 2022. In the full recording on Neuronline, Henriette van Praag, Áine Kelly, David Jiménez-Pavón, and Swathi Gujral discussed different mechanisms by which exercise positively influences brain health and function across the lifespan, from modulation of inflammation to regulation of adult neurogenesis. URL: https://community.sfn.org/index.php?/topic/5207-extended-qa-exercise-in-brain-health-and-disease/ How to Advocate for Mental Health Research In this panel, NMH Director Joshua Gordon, Maria Oquendo, Pat Kobor, Patricia Conrod, and Lori McMahon address current foundational research on mental health issues, advocacy efforts to increase public awareness and funding, and how the COVID-19 pandemic heightened the importance of addressing mental health across all ages. URL: https://neuronline.sfn.org/advocacy/how-to-advocate-for-mental-health-research How Models Clarify Our Understanding of the Brain Stephen Grossberg illustrates the importance of neural models by taking a close look at the stability-plasticity dilemma, and how neural models can help answer questions such as, how do we learn things quickly but remember them for a long time, or why does a fast-learning rate not force a fast-forgetting rate? URL: https://neuronline.sfn.org/scientific-research/how-models-clarify-our-understanding-of-the-brain How Science Communication Can Improve Your Career Effective science communication refers to the ability to discuss science in terms that your audience will understand. Read how scientists can communicate inwardly to colleagues, or outwardly with important stakeholders such as the public, government, industry, educators, or even scientists outside of one’s field. URL: https://neuronline.sfn.org/outreach/how-science-communication-can-improve-your-career
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Meet the Expert: Communicating on the Fly — What Neural Circuit Computations in Drosophila Can Teach Us About Our Own Brains
Bianca Williams posted an event in Community Calendar
untilRegister Here! Mala Murthy will highlight discoveries from her lab on the neural mechanisms and computations underlying social communication in the Drosophila model system and the many parallels with communication strategies in other animals, including humans. She will explain the important role of developing quantitative tools for studying behavior. She will also discuss the choices that led her and her lab down this research path and the role of effective communication in science. -
Meet the Expert: Building Things in Brains: Chemistry Construction Projects for Analysis and Discovery in Neural Systems
Bianca Williams posted an event in Community Calendar
untilRegister Here! Over the past seven years, an in situ chemical synthesis approach to biological systems has emerged, in which functional materials are assembled within tissues such as the brain – either constructed throughout the intact tissue (hydrogel-tissue chemistry/HTC), or genetically targeted to cell types (genetically-targeted chemical assembly/GTCA). Resulting hybrid materials are endowed with diverse capabilities, including anchoring and labeling of RNA and protein, in situ sequencing, transparency, reversible size changes, and electrical insulation or conduction. -
Meet the Expert: Studying Both Sexes in a World Built Around the Male Brain
Bianca Williams posted an event in Community Calendar
untilRegister Here! Rebecca Shansky’s research investigates sexual dimorphism in fear circuitry using rodent models. Shansky’s lab integrates sophisticated behavioral analyses with high-resolution fluorescent microscopy to identify sex-specific patterns of fear expression, learning, and structural plasticity. She will discuss the challenges and surprises she’s encountered as a sex differences-focused behavioral neuroscientist, as well as her current advocacy for sex equity in animal research.