With the rapid development of large-scale neural recording technologies, there is a need for modern statistical methods to dissect and interpret neural recordings. Byron Yu will describe how dimensionality reduction and related methods can be applied to large-scale neural recordings to provide new insights about brain function. He will also discuss the benefits of quantitative and experimental scientists working together at every stage of the scientific process: from experimental conception and design, to data analysis, to development of new statistical tools, and beyond.